Expression and clinical significance of PD-L1, B7-H3, B7-H4 and TILs in human small cell lung Cancer (SCLC)

BACKGROUND: Small cell lung cancer (SCLC) accounts for 10–15% of all lung malignancies and its prognosis is dismal. Although early studies have shown promising clinical activity of immune checkpoint blockers, the immune composition and expression of potentially actionable immunostimulatory targets i...

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Vydáno v:J Immunother Cancer
Hlavní autoři: Carvajal-Hausdorf, Daniel, Altan, Mehmet, Velcheti, Vamsidhar, Gettinger, Scott N., Herbst, Roy S., Rimm, David L., Schalper, Kurt A.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6408760/
https://ncbi.nlm.nih.gov/pubmed/30850021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0540-1
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