Functional relevance of the multi-drug transporter abcg2 on teriflunomide therapy in an animal model of multiple sclerosis

BACKGROUND: The multi-drug resistance transporter ABCG2, a member of the ATP-binding cassette (ABC) transporter family, mediates the efflux of different immunotherapeutics used in multiple sclerosis (MS), e.g., teriflunomide (teri), cladribine, and mitoxantrone, across cell membranes and organelles....

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Detaylı Bibliyografya
Yayımlandı:J Neuroinflammation
Asıl Yazarlar: Thiele née Schrewe, Lisa, Guse, Kirsten, Tietz, Silvia, Remlinger, Jana, Demir, Seray, Pedreiturria, Xiomara, Hoepner, Robert, Salmen, Anke, Pistor, Maximilian, Turner, Timothy, Engelhardt, Britta, Hermann, Dirk M., Lühder, Fred, Wiese, Stefan, Chan, Andrew
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2020
Konular:
Short Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6951012/
https://ncbi.nlm.nih.gov/pubmed/31915017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1677-z
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