Teriflunomide and monomethylfumarate target HIV-induced neuroinflammation and neurotoxicity

HIV-associated neurocognitive disorders (HAND) affect about 50% of infected patients despite combined antiretroviral therapy (cART). Ongoing compartmentalized inflammation mediated by microglia which are activated by HIV-infected monocytes has been postulated to contribute to neurotoxicity independe...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Ambrosius, Björn, Faissner, Simon, Guse, Kirsten, von Lehe, Marec, Grunwald, Thomas, Gold, Ralf, Grewe, Bastian, Chan, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346211/
https://ncbi.nlm.nih.gov/pubmed/28284222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-0829-2
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