Clozapine Regulates Microglia and Is Effective in Chronic Experimental Autoimmune Encephalomyelitis

OBJECTIVE: Progressive multiple sclerosis is characterized by chronic inflammation with microglial activation, oxidative stress, accumulation of iron and continuous neurodegeneration with inadequate effectiveness of medications used so far. We now investigated effects of iron on microglia and used t...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Ceylan, Ulaş, Haupeltshofer, Steffen, Kämper, Laura, Dann, Justus, Ambrosius, Björn, Gold, Ralf, Faissner, Simon
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8126707/
https://ncbi.nlm.nih.gov/pubmed/34012440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.656941
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