Clozapine Regulates Microglia and Is Effective in Chronic Experimental Autoimmune Encephalomyelitis

OBJECTIVE: Progressive multiple sclerosis is characterized by chronic inflammation with microglial activation, oxidative stress, accumulation of iron and continuous neurodegeneration with inadequate effectiveness of medications used so far. We now investigated effects of iron on microglia and used t...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Ceylan, Ulaş, Haupeltshofer, Steffen, Kämper, Laura, Dann, Justus, Ambrosius, Björn, Gold, Ralf, Faissner, Simon
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8126707/
https://ncbi.nlm.nih.gov/pubmed/34012440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.656941
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