Clozapine Regulates Microglia and Is Effective in Chronic Experimental Autoimmune Encephalomyelitis

OBJECTIVE: Progressive multiple sclerosis is characterized by chronic inflammation with microglial activation, oxidative stress, accumulation of iron and continuous neurodegeneration with inadequate effectiveness of medications used so far. We now investigated effects of iron on microglia and used t...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Ceylan, Ulaş, Haupeltshofer, Steffen, Kämper, Laura, Dann, Justus, Ambrosius, Björn, Gold, Ralf, Faissner, Simon
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8126707/
https://ncbi.nlm.nih.gov/pubmed/34012440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.656941
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