Contribution of GABAergic interneurons to amyloid-β plaque pathology in an APP knock-in mouse model

The amyloid-β (Aβ) peptide, the primary constituent of amyloid plaques found in Alzheimer’s disease (AD) brains, is derived from sequential proteolytic processing of the Amyloid Precursor Protein (APP). However, the contribution of different cell types to Aβ deposition has not yet been examined in a...

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Bibliografski detalji
Izdano u:Mol Neurodegener
Glavni autori: Rice, Heather C., Marcassa, Gabriele, Chrysidou, Iordana, Horré, Katrien, Young-Pearse, Tracy L., Müller, Ulrike C., Saito, Takashi, Saido, Takaomi C., Vassar, Robert, de Wit, Joris, De Strooper, Bart
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Short Report
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6950898/
https://ncbi.nlm.nih.gov/pubmed/31915042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-019-0356-y
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