Llwytho...
Increased Insoluble Amyloid-β Induces Negligible Cognitive Deficits in Old App(NL/NL) Knock-In Mice
Commonly used Alzheimer’s disease mouse models are based on the ectopic overexpression of the human amyloid precursor protein (APP) gene, together with a mutant presenilin gene. Surprisingly, humanized APP knock-in mouse models carrying a single APP Swedish mutation (App(NL)), failed to develop amyl...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | J Alzheimers Dis |
|---|---|
| Prif Awduron: | , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
IOS Press
2018
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6218137/ https://ncbi.nlm.nih.gov/pubmed/30320577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-180410 |
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