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The two faces of synaptic failure in App(NL-G-F) knock-in mice

BACKGROUND: Intensive basic and preclinical research into Alzheimer’s disease (AD) has yielded important new findings, but they could not yet been translated into effective therapies. One of the reasons is the lack of animal models that sufficiently reproduce the complexity of human AD and the respo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Alzheimers Res Ther
Hauptverfasser: Latif-Hernandez, Amira, Sabanov, Victor, Ahmed, Tariq, Craessaerts, Katleen, Saito, Takashi, Saido, Takaomi, Balschun, Detlef
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7445922/
https://ncbi.nlm.nih.gov/pubmed/32838792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-020-00667-6
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