Contribution of GABAergic interneurons to amyloid-β plaque pathology in an APP knock-in mouse model

The amyloid-β (Aβ) peptide, the primary constituent of amyloid plaques found in Alzheimer’s disease (AD) brains, is derived from sequential proteolytic processing of the Amyloid Precursor Protein (APP). However, the contribution of different cell types to Aβ deposition has not yet been examined in a...

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Bibliografiske detaljer
Udgivet i:Mol Neurodegener
Main Authors: Rice, Heather C., Marcassa, Gabriele, Chrysidou, Iordana, Horré, Katrien, Young-Pearse, Tracy L., Müller, Ulrike C., Saito, Takashi, Saido, Takaomi C., Vassar, Robert, de Wit, Joris, De Strooper, Bart
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Short Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6950898/
https://ncbi.nlm.nih.gov/pubmed/31915042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-019-0356-y
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