Contribution of GABAergic interneurons to amyloid-β plaque pathology in an APP knock-in mouse model

The amyloid-β (Aβ) peptide, the primary constituent of amyloid plaques found in Alzheimer’s disease (AD) brains, is derived from sequential proteolytic processing of the Amyloid Precursor Protein (APP). However, the contribution of different cell types to Aβ deposition has not yet been examined in a...

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Detalhes bibliográficos
Publicado no:Mol Neurodegener
Main Authors: Rice, Heather C., Marcassa, Gabriele, Chrysidou, Iordana, Horré, Katrien, Young-Pearse, Tracy L., Müller, Ulrike C., Saito, Takashi, Saido, Takaomi C., Vassar, Robert, de Wit, Joris, De Strooper, Bart
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6950898/
https://ncbi.nlm.nih.gov/pubmed/31915042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-019-0356-y
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