Validation and Clinical Application of a Novel LC-MS Method for Quantification of Dolutegravir in Breast Milk

BACKGROUND: A novel, sensitive and reproducible method for quantification of dolutegravir (DTG) in dried breast milk spots (DBMS) was developed and validated for use in clinical studies. Its application enabled measurement of DTG pharmacokinetics in breastfeeding mothers and their infants. RESULTS/M...

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Gepubliceerd in:Bioanalysis
Hoofdauteurs: Gini, J, Penchala, SD, Amara, A, Challenger, E, Egan, D, Waitt, C, Lamorde, M, Orrell, C, Myer, L, Khoo, S, Else, LJ
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6949129/
https://ncbi.nlm.nih.gov/pubmed/30450920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/bio-2018-0085
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