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Validation and Clinical Application of a Novel LC-MS Method for Quantification of Dolutegravir in Breast Milk

BACKGROUND: A novel, sensitive and reproducible method for quantification of dolutegravir (DTG) in dried breast milk spots (DBMS) was developed and validated for use in clinical studies. Its application enabled measurement of DTG pharmacokinetics in breastfeeding mothers and their infants. RESULTS/M...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Bioanalysis
Prif Awduron: Gini, J, Penchala, SD, Amara, A, Challenger, E, Egan, D, Waitt, C, Lamorde, M, Orrell, C, Myer, L, Khoo, S, Else, LJ
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6949129/
https://ncbi.nlm.nih.gov/pubmed/30450920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/bio-2018-0085
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