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Validation and Clinical Application of a Novel LC-MS Method for Quantification of Dolutegravir in Breast Milk

BACKGROUND: A novel, sensitive and reproducible method for quantification of dolutegravir (DTG) in dried breast milk spots (DBMS) was developed and validated for use in clinical studies. Its application enabled measurement of DTG pharmacokinetics in breastfeeding mothers and their infants. RESULTS/M...

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發表在:Bioanalysis
Main Authors: Gini, J, Penchala, SD, Amara, A, Challenger, E, Egan, D, Waitt, C, Lamorde, M, Orrell, C, Myer, L, Khoo, S, Else, LJ
格式: Artigo
語言:Inglês
出版: 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6949129/
https://ncbi.nlm.nih.gov/pubmed/30450920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/bio-2018-0085
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