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Development and validation of an LC-MS/MS assay for the quantification of dolutegravir extracted from human hair

Measurement of drug concentrations in hair provides a non-invasive approach to assess drug adherence. Here, we report on the development and validation of a method for the quantification of the antiretroviral dolutegravir (DTG) extracted from human hair. DTG is extracted from hair samples by sonicat...

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Detalhes bibliográficos
Publicado no:Anal Bioanal Chem
Main Authors: Sykes, Craig, Blake, Kimberly, White, Nicole, Schauer, Amanda P, Guzman, Bryan B., Cottrell, Mackenzie L, Tamraz, Bani, Kashuba, Angela DM
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6501839/
https://ncbi.nlm.nih.gov/pubmed/30280227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-018-1394-y
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