Validation and Clinical Application of a Novel LC-MS Method for Quantification of Dolutegravir in Breast Milk

BACKGROUND: A novel, sensitive and reproducible method for quantification of dolutegravir (DTG) in dried breast milk spots (DBMS) was developed and validated for use in clinical studies. Its application enabled measurement of DTG pharmacokinetics in breastfeeding mothers and their infants. RESULTS/M...

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Dettagli Bibliografici
Pubblicato in:Bioanalysis
Autori principali: Gini, J, Penchala, SD, Amara, A, Challenger, E, Egan, D, Waitt, C, Lamorde, M, Orrell, C, Myer, L, Khoo, S, Else, LJ
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6949129/
https://ncbi.nlm.nih.gov/pubmed/30450920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/bio-2018-0085
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