Dectin-1 genetic deficiency predicts chronic lung allograft dysfunction and death

BACKGROUND: Innate immune activation impacts lung transplant outcomes. Dectin-1 is an innate receptor important for pathogen recognition. We hypothesized that genotypes reducing dectin-1 activity would be associated with infection, graft dysfunction, and death in lung transplant recipients. METHODS:...

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Udgivet i:JCI Insight
Main Authors: Calabrese, Daniel R., Wang, Ping, Chong, Tiffany, Hoover, Jonathan, Singer, Jonathan P., Torgerson, Dara, Hays, Steven R., Golden, Jeffrey A., Kukreja, Jasleen, Dugger, Daniel, Christie, Jason D., Greenland, John R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2019
Fag:
Clinical Medicine
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948872/
https://ncbi.nlm.nih.gov/pubmed/31613800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.133083
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