Dectin-1 genetic deficiency predicts chronic lung allograft dysfunction and death

BACKGROUND: Innate immune activation impacts lung transplant outcomes. Dectin-1 is an innate receptor important for pathogen recognition. We hypothesized that genotypes reducing dectin-1 activity would be associated with infection, graft dysfunction, and death in lung transplant recipients. METHODS:...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:JCI Insight
मुख्य लेखकों: Calabrese, Daniel R., Wang, Ping, Chong, Tiffany, Hoover, Jonathan, Singer, Jonathan P., Torgerson, Dara, Hays, Steven R., Golden, Jeffrey A., Kukreja, Jasleen, Dugger, Daniel, Christie, Jason D., Greenland, John R.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Clinical Investigation 2019
विषय:
Clinical Medicine
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948872/
https://ncbi.nlm.nih.gov/pubmed/31613800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.133083
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