Suppressed calcineurin-dependent gene expression identifies lung allograft recipients at increased risk of infection

Lung transplant immunosuppression regimens generally include the calcineurin inhibitor tacrolimus. We hypothesized that mean residual expression (MRE) of calcineurin-dependent genes assesses rejection and infection risk better than tacrolimus trough. We prospectively followed 44 lung allograft recip...

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Pubblicato in:Am J Transplant
Autori principali: Greenland, John R, Chong, Tiffany, Wang, Angelia S, Martinez, Emily, Shrestha, Pavan, Kukreja, Jasleen, Hays, Steven R., Golden, Jeffrey A, Singer, Jonathan P, Tang, Qizhi
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6699504/
https://ncbi.nlm.nih.gov/pubmed/29673076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.14886
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