Donor-reactive regulatory T cell frequency increases during acute cellular rejection of lung allografts

BACKGROUND: Acute cellular rejection is a major cause of morbidity following lung transplantation. Because regulatory T cells (Treg) limit rejection of solid organs, we hypothesized that donor-reactive Treg increase after transplantation with development of partial tolerance and decrease relative to...

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Detalhes bibliográficos
Publicado no:Transplantation
Main Authors: Greenland, John R, Wong, Charissa M, Ahuja, Rahul, Wang, Angelia S, Uchida, Chiyo, Golden, Jeffrey A, Hays, Steven R, Leard, Lorriana E, Rajalingam, Raja, Singer, Jonathan P, Kukreja, Jasleen, Wolters, Paul J, Caughey, George H, Tang, Qizhi
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5030122/
https://ncbi.nlm.nih.gov/pubmed/27077597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000001191
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