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Short Lung Transplant Donor Telomere Length is Associated with Decreased CLAD-Free Survival

Telomere length (TL) decreases with cellular aging and biologic stressors. As advanced donor and recipient age are risk factors for chronic lung allograft dysfunction (CLAD), we hypothesized that decreased age-adjusted donor TL would predict earlier onset of CLAD. Shorter donor TL was associated wit...

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Detalhes bibliográficos
Publicado no:Thorax
Main Authors: Faust, Hilary E, Golden, Jeff A, Rajalingam, Raja, Wang, Angelia S, Green, Gary, Hays, Steven R, Kukreja, Jasleen, Singer, Jonathan P, Wolters, Paul J, Greenland, John R
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550329/
https://ncbi.nlm.nih.gov/pubmed/28446663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2016-209897
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