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Short Lung Transplant Donor Telomere Length is Associated with Decreased CLAD-Free Survival

Telomere length (TL) decreases with cellular aging and biologic stressors. As advanced donor and recipient age are risk factors for chronic lung allograft dysfunction (CLAD), we hypothesized that decreased age-adjusted donor TL would predict earlier onset of CLAD. Shorter donor TL was associated wit...

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Pubblicato in:Thorax
Autori principali: Faust, Hilary E, Golden, Jeff A, Rajalingam, Raja, Wang, Angelia S, Green, Gary, Hays, Steven R, Kukreja, Jasleen, Singer, Jonathan P, Wolters, Paul J, Greenland, John R
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550329/
https://ncbi.nlm.nih.gov/pubmed/28446663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2016-209897
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