Short Lung Transplant Donor Telomere Length is Associated with Decreased CLAD-Free Survival

Telomere length (TL) decreases with cellular aging and biologic stressors. As advanced donor and recipient age are risk factors for chronic lung allograft dysfunction (CLAD), we hypothesized that decreased age-adjusted donor TL would predict earlier onset of CLAD. Shorter donor TL was associated wit...

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Veröffentlicht in:Thorax
Hauptverfasser: Faust, Hilary E, Golden, Jeff A, Rajalingam, Raja, Wang, Angelia S, Green, Gary, Hays, Steven R, Kukreja, Jasleen, Singer, Jonathan P, Wolters, Paul J, Greenland, John R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550329/
https://ncbi.nlm.nih.gov/pubmed/28446663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2016-209897
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