Metronomic capecitabine as an immune modulator in glioblastoma patients reduces myeloid-derived suppressor cells

BACKGROUND: Myeloid-derived suppressor cells (MDSCs) are elevated in the circulation of patients with glioblastoma (GBM), present in tumor tissue, and associated with poor prognosis. While low-dose chemotherapy reduces MDSCs in preclinical models, the use of this strategy to reduce MDSCs in GBM pati...

詳細記述

保存先:
書誌詳細
出版年:JCI Insight
主要な著者: Peereboom, David M., Alban, Tyler J., Grabowski, Matthew M., Alvarado, Alvaro G., Otvos, Balint, Bayik, Defne, Roversi, Gustavo, McGraw, Mary, Huang, Pengjing, Mohammadi, Alireza M., Kornblum, Harley I., Radivoyevitch, Tomas, Ahluwalia, Manmeet S., Vogelbaum, Michael A., Lathia, Justin D.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2019
主題:
Clinical Medicine
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948860/
https://ncbi.nlm.nih.gov/pubmed/31600167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.130748
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