ACTR-09. TARGETING MYELOID DERIVED SUPPRESSOR CELLS: PHASE 0/1 TRIAL OF LOW DOSE CAPECITABINE + BEVACIZUMAB IN PATIENTS WITH RECURRENT GLIOBLASTOMA

BACKGROUND: Glioblastoma (GBM) creates an immunosuppressive environment that allows tumor growth. Myeloid derived suppressor cells (MDSCs) mediate immunosuppression in GBMs. MDSCs are up-regulated in the blood of GBM patients. We have developed a novel strategy to target GBM immunosuppression using...

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Publicado no:Neuro Oncol
Main Authors: Peereboom, David, Lathia, Justin, Alban, Tyler, Mohammadi, Alireza, Ahluwalia, Manmeet, Brewer, Cathy, Vogelbaum, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216163/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.044
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