IMMU-08. MODELING UPFRONT GLIOBLASTOMA SURGICAL RESECTION AND STEROID USE REVEALS IMMUNOSUPPRESSIVE CHANGES AND SUGGESTS THAT PERIPHERAL LYMPHOCYTE COUNTS ARE ASSOCIATED WITH TUMOR VOLUME AND PROGNOSIS

Glioblastoma (GBM) and its treatment produces systemic immunosuppression, which is being targeted by immunotherapies. However, it remains unclear how surgical resection and steroids specifically in GBM alter the immune system. To further explore this issue, immunocompetent C57Bl/6 mice were intracra...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Otvos, Balint, Alban, Tyler, Grabowski, Matthew, Bayik, Defne, Winkelman, Robert, Johnson, Sarah, Rabljenovic, Anja, Vogelbaum, Michael, Ahluwalia, Manmeet, Fecci, Peter, Lathia, Justin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651165/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.439
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