IMMU-08. MODELING UPFRONT GLIOBLASTOMA SURGICAL RESECTION AND STEROID USE REVEALS IMMUNOSUPPRESSIVE CHANGES AND SUGGESTS THAT PERIPHERAL LYMPHOCYTE COUNTS ARE ASSOCIATED WITH TUMOR VOLUME AND PROGNOSIS

Glioblastoma (GBM) and its treatment produces systemic immunosuppression, which is being targeted by immunotherapies. However, it remains unclear how surgical resection and steroids specifically in GBM alter the immune system. To further explore this issue, immunocompetent C57Bl/6 mice were intracra...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Otvos, Balint, Alban, Tyler, Grabowski, Matthew, Bayik, Defne, Winkelman, Robert, Johnson, Sarah, Rabljenovic, Anja, Vogelbaum, Michael, Ahluwalia, Manmeet, Fecci, Peter, Lathia, Justin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651165/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.439
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