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IMMU-08. MODELING UPFRONT GLIOBLASTOMA SURGICAL RESECTION AND STEROID USE REVEALS IMMUNOSUPPRESSIVE CHANGES AND SUGGESTS THAT PERIPHERAL LYMPHOCYTE COUNTS ARE ASSOCIATED WITH TUMOR VOLUME AND PROGNOSIS

Glioblastoma (GBM) and its treatment produces systemic immunosuppression, which is being targeted by immunotherapies. However, it remains unclear how surgical resection and steroids specifically in GBM alter the immune system. To further explore this issue, immunocompetent C57Bl/6 mice were intracra...

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Opis bibliograficzny
Wydane w:Neuro Oncol
Główni autorzy: Otvos, Balint, Alban, Tyler, Grabowski, Matthew, Bayik, Defne, Winkelman, Robert, Johnson, Sarah, Rabljenovic, Anja, Vogelbaum, Michael, Ahluwalia, Manmeet, Fecci, Peter, Lathia, Justin
Format: Artigo
Język:Inglês
Wydane: Oxford University Press 2020
Hasła przedmiotowe:
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651165/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.439
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