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2B4 but not PD-1 blockade improves mortality in septic animals with preexisting malignancy
In addition to its well-known beneficial effects for the treatment of several types of cancer, PD-1 blockade has shown encouraging results in preclinical models of sepsis and in a recent clinical trial in sepsis. Because cancer is the most common comorbidity in septic patients, here we aimed to dete...
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| Publicado no: | JCI Insight |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6948854/ https://ncbi.nlm.nih.gov/pubmed/31723059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.127867 |
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