Tumor-Specific T Cells Exacerbate Mortality and Immune Dysregulation during Sepsis

Sepsis induces significant immune dysregulation characterized by lymphocyte apoptosis and alterations in the cytokine milieu. Because cancer patients exhibit a ten-fold greater risk of developing sepsis compared to the general population, we aimed to understand how pre-existing malignancy alters sep...

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Bibliographic Details
Published in:J Immunol
Main Authors: Chen, Ching-wen, Bennion, Kelsey B., Swift, David A., Morrow, Kristen N., Zhang, Wenxiao, Oami, Takehiko, Coopersmith, Craig M., Ford, Mandy L.
Format: Artigo
Language:Inglês
Published: 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8121248/
https://ncbi.nlm.nih.gov/pubmed/33911005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000865
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