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Pre-existing malignancy abrogates the beneficial effects of CXCR4 blockade during sepsis
Patients with cancer are at an increased risk of developing and dying from sepsis. We previously reported that blockade of the chemokine receptor CXCR4 resulted in decreased CD4(+) T cell exhaustion and improved survival in a model of polymicrobial sepsis in previously healthy mice. Here, we sought...
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| Publicado no: | J Leukoc Biol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7262428/ https://ncbi.nlm.nih.gov/pubmed/31985098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.3A1019-502R |
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