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Pre-existing malignancy abrogates the beneficial effects of CXCR4 blockade during sepsis

Patients with cancer are at an increased risk of developing and dying from sepsis. We previously reported that blockade of the chemokine receptor CXCR4 resulted in decreased CD4(+) T cell exhaustion and improved survival in a model of polymicrobial sepsis in previously healthy mice. Here, we sought...

詳細記述

保存先:
書誌詳細
出版年:J Leukoc Biol
主要な著者: Zhang, Wenxiao, Chihade, Deena B., Xie, Jianfeng, Chen, Ching-wen, Ramonell, Kimberly M., Liang, Zhe, Coopersmith, Craig
M., Ford, Mandy L.
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7262428/
https://ncbi.nlm.nih.gov/pubmed/31985098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.3A1019-502R
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