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Pre-existing malignancy abrogates the beneficial effects of CXCR4 blockade during sepsis
Patients with cancer are at an increased risk of developing and dying from sepsis. We previously reported that blockade of the chemokine receptor CXCR4 resulted in decreased CD4(+) T cell exhaustion and improved survival in a model of polymicrobial sepsis in previously healthy mice. Here, we sought...
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| 出版年: | J Leukoc Biol |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7262428/ https://ncbi.nlm.nih.gov/pubmed/31985098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.3A1019-502R |
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