O-GlcNAc transferase suppresses necroptosis and liver fibrosis

Worldwide, over a billion people suffer from chronic liver diseases, which often lead to fibrosis and then cirrhosis. Treatments for fibrosis remain experimental, in part because no unifying mechanism has been identified that initiates liver fibrosis. Necroptosis has been implicated in multiple live...

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Vydáno v:JCI Insight
Hlavní autoři: Zhang, Bichen, Li, Min-Dian, Yin, Ruonan, Liu, Yuyang, Yang, Yunfan, Mitchell-Richards, Kisha A., Nam, Jin Hyun, Li, Rui, Wang, Li, Iwakiri, Yasuko, Chung, Dongjun, Robert, Marie E., Ehrlich, Barbara E., Bennett, Anton M., Yu, Jun, Nathanson, Michael H., Yang, Xiaoyong
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948774/
https://ncbi.nlm.nih.gov/pubmed/31672932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.127709
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