O-GlcNAc Transferase Is Involved in Glucocorticoid Receptor-mediated Transrepression

Recruitment of O-GlcNAc transferase (OGT) to promoters plays an important role in gene repression. Glucocorticoid signaling represses the transcriptional activities of NF-κB and AP-1 through direct binding, yet the molecular mechanisms remain to be elucidated. Here we report that OGT is an important...

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Hlavní autoři: Li, Min-Dian, Ruan, Hai-Bin, Singh, Jay P., Zhao, Lin, Zhao, Tingting, Azarhoush, Sascha, Wu, Jing, Evans, Ronald M., Yang, Xiaoyong
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
Gene Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339970/
https://ncbi.nlm.nih.gov/pubmed/22371499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.303792
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