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O-GlcNAc transferase enables AgRP neurons to suppress browning of white fat

Induction of beige cells causes the browning of white fat and improves energy metabolism. However, the central mechanism that controls adipose tissue browning and its physiological relevance are largely unknown. Here we demonstrate that fasting and chemical-genetic activation of orexigenic AgRP neur...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Ruan, Hai-Bin, Dietrich, Marcelo O., Liu, Zhong-Wu, Zimmer, Marcelo R., Li, Min-Dian, Singh, Jay Prakash, Zhang, Kaisi, Yin, Ruonan, Wu, Jing, Horvath, Tamas L., Yang, Xiaoyong
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509746/
https://ncbi.nlm.nih.gov/pubmed/25303527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.09.010
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