O-GlcNAc transferase enables AgRP neurons to suppress browning of white fat

Induction of beige cells causes the browning of white fat and improves energy metabolism. However, the central mechanism that controls adipose tissue browning and its physiological relevance are largely unknown. Here we demonstrate that fasting and chemical-genetic activation of orexigenic AgRP neur...

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Pubblicato in:Cell
Autori principali: Ruan, Hai-Bin, Dietrich, Marcelo O., Liu, Zhong-Wu, Zimmer, Marcelo R., Li, Min-Dian, Singh, Jay Prakash, Zhang, Kaisi, Yin, Ruonan, Wu, Jing, Horvath, Tamas L., Yang, Xiaoyong
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509746/
https://ncbi.nlm.nih.gov/pubmed/25303527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.09.010
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