O-GlcNAc transferase suppresses necroptosis and liver fibrosis

Worldwide, over a billion people suffer from chronic liver diseases, which often lead to fibrosis and then cirrhosis. Treatments for fibrosis remain experimental, in part because no unifying mechanism has been identified that initiates liver fibrosis. Necroptosis has been implicated in multiple live...

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發表在:JCI Insight
Main Authors: Zhang, Bichen, Li, Min-Dian, Yin, Ruonan, Liu, Yuyang, Yang, Yunfan, Mitchell-Richards, Kisha A., Nam, Jin Hyun, Li, Rui, Wang, Li, Iwakiri, Yasuko, Chung, Dongjun, Robert, Marie E., Ehrlich, Barbara E., Bennett, Anton M., Yu, Jun, Nathanson, Michael H., Yang, Xiaoyong
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2019
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948774/
https://ncbi.nlm.nih.gov/pubmed/31672932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.127709
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