O-GlcNAc transferase suppresses necroptosis and liver fibrosis

Worldwide, over a billion people suffer from chronic liver diseases, which often lead to fibrosis and then cirrhosis. Treatments for fibrosis remain experimental, in part because no unifying mechanism has been identified that initiates liver fibrosis. Necroptosis has been implicated in multiple live...

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Dettagli Bibliografici
Pubblicato in:JCI Insight
Autori principali: Zhang, Bichen, Li, Min-Dian, Yin, Ruonan, Liu, Yuyang, Yang, Yunfan, Mitchell-Richards, Kisha A., Nam, Jin Hyun, Li, Rui, Wang, Li, Iwakiri, Yasuko, Chung, Dongjun, Robert, Marie E., Ehrlich, Barbara E., Bennett, Anton M., Yu, Jun, Nathanson, Michael H., Yang, Xiaoyong
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2019
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948774/
https://ncbi.nlm.nih.gov/pubmed/31672932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.127709
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