O-GlcNAc transferase suppresses necroptosis and liver fibrosis

Worldwide, over a billion people suffer from chronic liver diseases, which often lead to fibrosis and then cirrhosis. Treatments for fibrosis remain experimental, in part because no unifying mechanism has been identified that initiates liver fibrosis. Necroptosis has been implicated in multiple live...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Zhang, Bichen, Li, Min-Dian, Yin, Ruonan, Liu, Yuyang, Yang, Yunfan, Mitchell-Richards, Kisha A., Nam, Jin Hyun, Li, Rui, Wang, Li, Iwakiri, Yasuko, Chung, Dongjun, Robert, Marie E., Ehrlich, Barbara E., Bennett, Anton M., Yu, Jun, Nathanson, Michael H., Yang, Xiaoyong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948774/
https://ncbi.nlm.nih.gov/pubmed/31672932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.127709
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