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Amino acids license kinase mTORC1 activity and Treg cell function via small G proteins Rag and Rheb

Regulatory T (Treg) cells are critical mediators of immune tolerance whose activity depends upon T cell receptor (TCR) and mTORC1 kinase signaling, but the mechanisms that dictate functional activation of these pathways are incompletely understood. Here, we showed that amino acids license Treg cell...

詳細記述

保存先:
書誌詳細
出版年:Immunity
主要な著者: Shi, Hao, Chapman, Nicole M., Wen, Jing, Guy, Cliff, Long, Lingyun, Dhungana, Yogesh, Rankin, Sherri, Pelletier, Stephane, Vogel, Peter, Wang, Hong, Peng, Junmin, Guan, Kun-Liang, Chi, Hongbo
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948188/
https://ncbi.nlm.nih.gov/pubmed/31668641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2019.10.001
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