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Amino acids license kinase mTORC1 activity and Treg cell function via small G proteins Rag and Rheb
Regulatory T (Treg) cells are critical mediators of immune tolerance whose activity depends upon T cell receptor (TCR) and mTORC1 kinase signaling, but the mechanisms that dictate functional activation of these pathways are incompletely understood. Here, we showed that amino acids license Treg cell...
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| Pubblicato in: | Immunity |
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| Autori principali: | , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6948188/ https://ncbi.nlm.nih.gov/pubmed/31668641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2019.10.001 |
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