Leading Edge or Tumor Core: Intratumor Cancer Stem Cell Niches in Oral Cavity Squamous Cell Carcinoma and their Association with Stem Cell Function

OBJECTIVES: To describe differences in cancer stem cell (CSC) presence and behavior associated with their intratumor compartment of origin using a patient-derived xenograft (PDX) model of oral cavity squamous cell carcinoma (OCSCC). MATERIALS AND METHODS: Four HPV-negative OCSCC PDX cases were selec...

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Vydáno v:Oral Oncol
Hlavní autoři: Chowdhury, Farshad N., Reisinger, Julie, Gomez, Karina E., Chimed, Tugs-Saikhan, Thomas, Carissa M., Le, Phuong N., Miller, Bettina, Morton, John J., Nieto, Cera M., Somerset, Hilary L., Wang, Xiao-Jing, Keysar, Stephen B., Jimeno, Antonio
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948018/
https://ncbi.nlm.nih.gov/pubmed/31586893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.oraloncology.2019.09.011
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