The Role of RNA in HIV-1 Vif-Mediated Degradation of APOBEC3H

As many as five members of the APOBEC3 family of DNA cytosine deaminases are capable of inhibiting HIV-1 replication by deaminating viral cDNA cytosines and interfering with reverse transcription. HIV-1 counteracts restriction with the virally encoded Vif protein, which forms a hybrid ubiquitin liga...

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Udgivet i:J Mol Biol
Main Authors: Wang, Jiayi, Becker, Jordan T., Shi, Ke, Lauer, Kate V., Salamango, Daniel J., Aihara, Hideki, Shaban, Nadine M., Harris, Reuben S.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948013/
https://ncbi.nlm.nih.gov/pubmed/31628948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2019.09.014
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