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The Role of RNA in HIV-1 Vif-Mediated Degradation of APOBEC3H
As many as five members of the APOBEC3 family of DNA cytosine deaminases are capable of inhibiting HIV-1 replication by deaminating viral cDNA cytosines and interfering with reverse transcription. HIV-1 counteracts restriction with the virally encoded Vif protein, which forms a hybrid ubiquitin liga...
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| Veröffentlicht in: | J Mol Biol |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6948013/ https://ncbi.nlm.nih.gov/pubmed/31628948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2019.09.014 |
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