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Characterization of monoclonal antibodies generated to the 287–302 amino acid loop of the human epidermal growth factor receptor

Background: The dysregulation of epidermal growth factor receptor (EGFR) has been implicated in the oncogenesis of various malignancies including glioblastoma and some epithelial cancers. Oncogenesis occurs from the overexpression of EGFR, often linked to gene amplification or receptor mutagenesis....

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Antib Ther
Prif Awduron: Ho, Eric Chun Hei, Antignani, Antonella, Sarnovsky, Robert, FitzGerald, David
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6947844/
https://ncbi.nlm.nih.gov/pubmed/31934685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/abt/tbz011
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