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Characterization of monoclonal antibodies generated to the 287–302 amino acid loop of the human epidermal growth factor receptor

Background: The dysregulation of epidermal growth factor receptor (EGFR) has been implicated in the oncogenesis of various malignancies including glioblastoma and some epithelial cancers. Oncogenesis occurs from the overexpression of EGFR, often linked to gene amplification or receptor mutagenesis....

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Publicat a:Antib Ther
Autors principals: Ho, Eric Chun Hei, Antignani, Antonella, Sarnovsky, Robert, FitzGerald, David
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6947844/
https://ncbi.nlm.nih.gov/pubmed/31934685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/abt/tbz011
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