Analysis of Pseudomonas exotoxin activation and conformational changes by using monoclonal antibodies as probes.
Pseudomonas exotoxin (PE) is a protein toxin composed of three structural domains. In its native form, the toxin is a 66,000-Mr proenzyme that must be activated to express full ADP-ribosylating activity. To study the process of activation and accompanying conformational changes, we have isolated 10...
Uloženo v:
| Vydáno v: | Infect Immun |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology (ASM)
1991
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257755/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1702764/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.1.407-414.1991 |
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