ロード中...

Generation of antibody-based therapeutics targeting the idiotype of B-cell malignancies

BACKGROUND: A feature of many B-cell tumors is a surface-expressed immunoglobulin (sIg). The complementarity-determining regions (CDRs) of the sIg, termed the ‘idiotype’, are unique to each tumor. We report on a phage selection strategy to generate anti-idiotype therapeutics that reacts with sIg CDR...

詳細記述

保存先:
書誌詳細
出版年:Antib Ther
主要な著者: Weiss, Emily, Sarnovsky, Robert, Ho, Mitchell, Arons, Evgeny, Kreitman, Robert, Angelus, Evan, Antignani, Antonella, FitzGerald, David
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6383771/
https://ncbi.nlm.nih.gov/pubmed/30801054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/abt/tby012
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!