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Treatment of Hematologic Malignancies with Immunotoxins and Antibody-drug Conjugates

To enable antibodies to function as cytotoxic anticancer agents, they are modified either via attachment to protein toxins or highly potent small molecular weight drugs. Such molecules, termed immunotoxins and antibody drug conjugates respectively, represent a second revolution in antibody-mediated...

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Detalhes bibliográficos
Main Authors: FitzGerald, David J., Wayne, Alan S., Kreitman, Robert J., Pastan, Ira
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201758/
https://ncbi.nlm.nih.gov/pubmed/21998010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-1374
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