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Treatment of Hematologic Malignancies with Immunotoxins and Antibody-drug Conjugates

To enable antibodies to function as cytotoxic anticancer agents, they are modified either via attachment to protein toxins or highly potent small molecular weight drugs. Such molecules, termed immunotoxins and antibody drug conjugates respectively, represent a second revolution in antibody-mediated...

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Podrobná bibliografie
Hlavní autoři: FitzGerald, David J., Wayne, Alan S., Kreitman, Robert J., Pastan, Ira
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201758/
https://ncbi.nlm.nih.gov/pubmed/21998010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-1374
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