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Characterization of monoclonal antibodies generated to the 287–302 amino acid loop of the human epidermal growth factor receptor

Background: The dysregulation of epidermal growth factor receptor (EGFR) has been implicated in the oncogenesis of various malignancies including glioblastoma and some epithelial cancers. Oncogenesis occurs from the overexpression of EGFR, often linked to gene amplification or receptor mutagenesis....

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Detalhes bibliográficos
Publicado no:Antib Ther
Main Authors: Ho, Eric Chun Hei, Antignani, Antonella, Sarnovsky, Robert, FitzGerald, David
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6947844/
https://ncbi.nlm.nih.gov/pubmed/31934685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/abt/tbz011
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