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Synthesis of (–)-Mitrephorone A via a Bio-inspired Late Stage C–H Oxidation of (–)-Mitrephorone B

We present a bio-inspired late stage C–H oxidation of the ent-trachylobane natural product mitrephorone B to mitrephorone A. The realization of this unprecedented transformation was accomplished by either an iron-catalyzed or electrochemical oxidation and enabled access to the densely substituted ox...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Wein, Lukas Anton, Wurst, Klaus, Angyal, Peter, Weisheit, Lara, Magauer, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6946608/
https://ncbi.nlm.nih.gov/pubmed/31770485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b11646
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