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Relationship between CpG island methylation phenotype, microsatellite instability phenotype and mutation of KRAS, NRAS, and BRAF genes in colorectal cancer

Objective: CpG island methylation phenotype (CIMP) and microsatellite instability (MSI) are two different molecular mechanisms in colorectal cancer (CRC). Proto-oncogene KRAS, mutations in NRAS and BRAF play an important role in the formation of colorectal cancer. The correlation between the molecul...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Pathol
Main Authors: Luo, Yu, Cheng, Bo, Liu, Shan, Xu, Lin, Wu, Xizhao, Sun, Suozhu
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6945156/
https://ncbi.nlm.nih.gov/pubmed/31933925
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