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Tetranucleotide and Low Microsatellite Instability Are Inversely Associated with the CpG Island Methylator Phenotype in Colorectal Cancer

SIMPLE SUMMARY: A type of DNA mismatch repair defect known as “elevated microsatellite alterations at selected tetranucleotide repeats” (EMAST) is found across many different cancers. Tetranucleotide microsatellite instability, which is caused by MSH3 mismatch repair gene/protein loss-of-function, s...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Meessen, Sabine, Currey, Nicola, Jahan, Zeenat, Parker, Hannah W., Jenkins, Mark A., Buchanan, Daniel D., Hopper, John L., Segelov, Eva, Dahlstrom, Jane E., Kohonen-Corish, Maija R. J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8308094/
https://ncbi.nlm.nih.gov/pubmed/34298744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13143529
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