Tetranucleotide and Low Microsatellite Instability Are Inversely Associated with the CpG Island Methylator Phenotype in Colorectal Cancer

SIMPLE SUMMARY: A type of DNA mismatch repair defect known as “elevated microsatellite alterations at selected tetranucleotide repeats” (EMAST) is found across many different cancers. Tetranucleotide microsatellite instability, which is caused by MSH3 mismatch repair gene/protein loss-of-function, s...

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Publicado en:Cancers (Basel)
Autores principales: Meessen, Sabine, Currey, Nicola, Jahan, Zeenat, Parker, Hannah W., Jenkins, Mark A., Buchanan, Daniel D., Hopper, John L., Segelov, Eva, Dahlstrom, Jane E., Kohonen-Corish, Maija R. J.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8308094/
https://ncbi.nlm.nih.gov/pubmed/34298744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13143529
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